Human IgE-binding factors.

G Delespesse; M Sarfati; H Hofstetter

doi:10.1016/0167-5699(89)90173-4

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PubMed · 2525913

Human IgE-binding factors.

G Delespesse·M Sarfati·H Hofstetter

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Abstract

The production of IgE antibodies is known to be regulated by isotype-specific mechanisms that are not antigen specific. During the last decade several studies have indicated that soluble factors with affinity for IgE (IgE-binding factors, IgE-BFs) may exert such a role by interacting with IgE-bearing B lymphocytes. In the human, some of these IgE-BFs appear to be identical to soluble CD23, a B-cell surface marker thought to be involved in the control of B-cell proliferation or differentiation. In this article, Guy Delespesse and colleagues summarize several new findings regarding the cellular origin, structure and function of IgE-BFs/sCD23.

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Antigens, Differentiation, B-Lymphocyte Humans Immunoglobulin E Interleukin-4 Interleukins Lymphokines Prostatic Secretory Proteins Receptors, Fc Receptors, IgE Journal Article Research Support, Non-U.S. Gov't Review

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G Delespesse, M Sarfati, H Hofstetter. 1989. Human IgE-binding factors.. https://doi.org/10.1016/0167-5699(89)90173-4

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