PubMed · 2463409
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V I Ivanov, I A Mikhaĭlova, S V Kolesnikov, V S Gurevich. 1988. [A device for studying platelet aggregation].. https://pubmed.ncbi.nlm.nih.gov/2463409/
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INTRODUCTION: Congential deficiency of factor V is a rare condition, transmitted in autosomal recessive way. Heterozygote patients generally have no symptoms, homozygotes present with spontaneous and postoperative bleedings. About one-half of patients are diagnosed in adulthood. METHODS: The presented case is a double heterozygote, which was confirmed using moleculare biological methods. The authors found many carriers in his family. CONCLUSIONS: This rare and sometimes severe disorder needs regular haematological controls. Carriers must have more attention during surgical procedures and labour, and the family doctor should be informed about there condition.
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