Differences between transfer RNA molecules.

W H McClain; H B Nicholas

doi:10.1016/0022-2836(87)90240-3

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Differences between transfer RNA molecules.

W H McClain·H B Nicholas

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Abstract

Computer-assisted comparisons of 67 tRNA sequences that function in Escherichia coli or Salmonella typhimurium were used to identify single and multiple nucleotide positions that maximally distinguish the 20 amino acid acceptor groups. Positions in the anticodon were identified most frequently, as expected from the decoding function of this region of the tRNA. The biological function, if any, of positions outside the anticodon may include specificity for aminoacyl-tRNA synthetase enzymes.

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Amino Acids Base Sequence Computers Escherichia coli Models, Molecular Molecular Sequence Data Nucleic Acid Conformation RNA, Bacterial RNA, Transfer Salmonella typhimurium Software Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

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W H McClain, H B Nicholas. 1987-04-20. Differences between transfer RNA molecules.. https://doi.org/10.1016/0022-2836(87)90240-3

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