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PubMed · 2261018

[Infant colic].

N B Jordán·C E Lugo
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Abstract

The literature regarding infantile colic is reviewed. It is characterized by difficulties in definition. Different theories have been implied as to its etiology: behavioral and developmental as well as gastrointestinal causes are considered. The management and treatment based on both theories were revised. Most of them have proven to be effective in many cases. We recognize that future research is needed so that better management and treatment can be designed and prepared for this condition.

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ColicFemaleGastrointestinal DiseasesHumansInfantInfant FoodInfant, NewbornMaleMother-Child RelationsEnglish AbstractJournal ArticleReview

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BibTeXRIS

N B Jordán, C E Lugo. 1990. [Infant colic].. https://pubmed.ncbi.nlm.nih.gov/2261018/

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PubMed2006

Reduction of crying episodes owing to infantile colic: A randomized controlled study on the efficacy of a new infant formula.

OBJECTIVES: The aim of this study was to evaluate the efficacy on crying episodes owing to infantile colic of a new infant formula containing partially hydrolysed whey proteins, prebiotic oligosaccharides (OS), with a high beta-palmitic acid content. DESIGN: Prospective randomized controlled study. SETTING: Italy. SUBJECTS: Two hundred and sixty-seven formula-fed infants, aged less than 4 months, with infantile colic, were randomized to receive either the new infant formula (study treatment (ST)) or a standard formula and simethicone (6 mg/kg twice a day) (control treatment (CT)). A questionnaire was given to parents to evaluate for 14 days the daily number of colic episodes and crying time. RESULTS: Out of the 199 infants who completed the study, 96 were treated with the new formula and 103 were not treated. Infants receiving the new formula had a significant decrease in colic episodes after 1 week (2.47+/-1.94 at day 7 vs 5.99+/-1.84 at the study entry) compared to infants receiving the CT (3.72+/-1.98 at day 7 vs 5.41+/-1.88 at the study entry) (P < 0.0001). Also at day 14, the crying episodes were significantly different between the two groups of infants (1.76+/-1.60 in ST vs 3.32+/-2.06 in CT) (P < 0.0001). CONCLUSIONS: The use of a partially hydrolysed formula supplemented with fructo- and galacto-OS induces a reduction of crying episodes in infants with colic after 7 and 14 days when compared with a standard formula and simethicone.

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