PubMed · 2011553
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P Holmes. Wrong remedy.. https://pubmed.ncbi.nlm.nih.gov/2011553/
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An automated chromatographic system, combining solid-phase extraction and automated pre-column exchange, is described for the routine determination of Zy 17617B at the pmol/ml level in human plasma. The sample extraction and elution onto the analytical column were performed automatically and concomitantly using a conventional liquid chromatographic apparatus equipped with a Merck OSP-2 on-line sample preparator. Validation data demonstrate the reliability of the method.
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