PubMed · 189657
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J Bitran, R K Desser, T R DeMeester, H M Golomb. 1977. Adriamycin-radiotherapy interaction.. https://doi.org/10.7326/0003-4819-86-1-117_1
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Eleven patients with measurable, previously treated oat-cell carcinoma of the lung received DDP 80 mg/m2 once every three weeks. The drug was given as a 6-hour infusion. In 4 patients a partial remission was achieved: 2 others showed a minor tumor regression. The main toxicity was vomiting, whereas generally myelosuppression and nephrotoxicity were manageable. Based on these preliminary data, a further investigation of DDP in the treatment of oat-cell carcinoma of the lung is definitely warranted.
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