PubMed · 1865911
Solid-phase gene assembly.
Abstract
New technologies for multiple chemical synthesis of oligonucleotides and stepwise hybridization on a solid-phase support enable the rapid and cost-effective preparation of long duplex DNA regions. Will these new technologies usher in a new era in protein engineering?
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K L Beattie, R F Fowler. 1991-08-08. Solid-phase gene assembly.. https://doi.org/10.1038/352548a0
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