Search PubMed⌕ Search

PubMed · 1725052

Thrombolysis, left ventricular function, and mortality.

Abstract

Coronary thrombolysis is now accepted as effective treatment for coronary thrombosis and myocardial infarction. The a priori hypotheses that thrombolysis works by restoring coronary patency and that coronary reperfusion preserves myocardial function have been disputed but not disproved. This report discusses the effects of reperfusion on ventricular function, the limitations of present techniques for assessing myocardial salvage, and the implications for future clinical studies of these limitations.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

D P de Bono. 1991. Thrombolysis, left ventricular function, and mortality.. https://pubmed.ncbi.nlm.nih.gov/1725052/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Two- and three-dimensional echocardiographic imaging of massive left intraventricular thrombosis complicating fatal heart failure.

These images describe a case of massive left ventricular (LV) thrombosis complicating fatal heart failure in a 61 year-old patient with history of myocardial infarction, apical aneurysm, and no previous evidence of LV thrombosis. Two-dimensional echocardiography showed that the thrombus obliterated 34% of LV volume at end-diastole. Three-dimensional echocardiography allowed higher definition of thrombus architecture and dimensions, revealing obliteration of 40% of LV volume at end-diastole. Careful assessment of thromboembolic risk to guide therapeutic decision making should be considered mandatory in subjects with a large extent of wall asynergy, even in those with no previous evidence of LV thrombosis. Three-dimensional echocardiography may be considered an accurate technique for the characterization of LV thrombi in these patients.

Coronary Thrombosis↗

Simultaneous multivessel acute drug-eluting stent thrombosis.

Stent thrombosis (ST) in the era of bare metal stents (BMS) using high-pressure stent deployment and combined anti-platelet therapy is an uncommon but feared complication. There is concern for an elevated risk of stent thrombosis (ST) with drug-eluting stents (DES). We describe a case of simultaneous multivessel drug-eluting stent thrombosis 8 h after deployment of paclitaxel-eluting stents in the right coronary (RCA) and left anterior descending (LAD) arteries.

Coronary Thrombosis↗