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PubMed · 17175952

[Does transrectal MRI before radical prostatectomy modify the operative technique to decrease the positive margin rate?].

Aurélien Descazeaud·Michael Peyromaure·Annick Vieillefond·Debré Bernard·Marc Zerbib
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Abstract

OBJECTIVE: To determine the value of magnetic resonance imaging (MRI) in the surgical management of prostate cancer patients. PATIENTS AND METHODS: 159 patients with prostate cancer underwent transrectal MRI before retropubic radical prostatectomy (RP). Patients operated despite a suspicion of extraprostatic extension on MRI had a modified non-nerve-sparing surgical technique. Postoperative histological findings were compared to MRI data. RESULTS: 34/159 patients (21.4%) had suspected extraprostatic extension in MRI. The pT3 rate on the RP specimen was significantly higher for patients with abnormal MRI than for patients with normal MRI (61% versus 39%, p = 0.02). Among pT3 patients, the positive surgical margin rate was significantly lower in the group with abnormal MRI than in the group with normal MRI (24% versus 51%, p = 0.035). CONCLUSIONS: Among patients with stage pT3 on the RP specimen, those in whom extraprostatic extension was suspected on MRI were treated by a modified surgical technique resulting in a lower positive surgical margin rate.

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AgedHumansMagnetic Resonance ImagingMaleMiddle AgedPreoperative CareProstatectomyProstatic NeoplasmsEnglish AbstractJournal Article

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Aurélien Descazeaud, Michael Peyromaure, Annick Vieillefond, Debré Bernard, Marc Zerbib. 2006. [Does transrectal MRI before radical prostatectomy modify the operative technique to decrease the positive margin rate?].. https://pubmed.ncbi.nlm.nih.gov/17175952/

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