PubMed · 16915136
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Margaret E O'Kane. 2006-01-09. How am I doing?. https://pubmed.ncbi.nlm.nih.gov/16915136/
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UNLABELLED: 99mTc-Mercaptoacetyltriglycine is used for dynamic renal imaging, and the summary of product characteristics (SPC) for the European formulation specifies a shelf life of 1 or 4 h, depending on the reconstitution volume of the kit. To minimize the time required to test the radiochemical purity, a simplified quality control method was developed. METHODS: To satisfy the recommendations of the International Commission on Harmonisation, results obtained with the methods described in the European and American SPCs were compared with those obtained with the simplified method. Further validation of the new method was performed by comparison with the standard 2-strip thin-layer chromatographic method as well as tests for linearity and limits of detection and quantification. RESULTS: The simplified method provided results comparable to those provided by the registered SPC methods but was more rapid to perform and used smaller volumes of solvents. CONCLUSION: The simplified method is a reasonable alternative to the registered SPC methods.
In summary, the AHRQ QIs are a set of readily available programs that can be downloaded without charge from the AHRQ Web site. The methodology is completely open and accessible to all users. The QI software can be applied to hospital administrative data that is available within individual institutions or from state data organizations and hospital associations and can provide valuable insights into health care quality at extremely low cost. The QIs have been incorporated into numerous quality assessment reports, including hospital-specific reports, with the aim of improving health care quality at a reasonable cost. With enhancements currently underway, the QIs will be an even more valuable part of the toolkit to improve health care quality in the United States.
Health care quality measurement is at least 250 years old. While the names and faces of the measures and measurees have changed, the intent of such measurement, i.e. obtaining data and information bearing clinical outcomes, has not changed over the years, and nor have the challenges associated with the measurement of quality in health care. Measurement is not a neutral activity. It evokes considerable anxiety and frustration among all concerned: those who are being measured, those who are doing the measuring, and those who are seeking the data for a variety of purposes. There is little agreement on the philosophy of measurement, on what to measure, on whether or how to adjust for what the patient brings to the clinical encounter, on how data should be analyzed, or on how to report the data; and of course the ultimate questions relate to the value of measurement. Measurement adds new costs to the health care delivery system. Tangible improvements in care, directly attributable to -performance measurement, are repeatedly being documented. However, the jury has not yet returned a verdict on whether performance measurement data are being used by stakeholders for better decision-making.