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Blocking the blue.

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P Hawse. 2006. Blocking the blue.. https://doi.org/10.1136/bjo.2006.095653

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A simple confocal fibre-optic laser method for intraocular lens power measurement.

PURPOSE: To develop novel confocal fibre-optic laser method (CFOLM) for accurate and objective measuring of the dioptric power of both positive and negative intraocular lenses (IOLs). METHODS: The CFOLM principle of operation is based on a simple apertureless single-mode fibre laser confocal design. The key element is a single-mode fibre coupler that serves simultaneously as a point light source (3-5 microm fibre diameter) used for the formation of a collimated Gaussian beam, and as a confocal point receiver that is highly sensitive to spatial displacements of the focused backreflectance laser emission. The basic CFOLM systems include IOL testing set-ups for the measurement of both positive and negative IOLs. RESULTS: The CFOLM designs provide high accuracy (<or=1 microm) in spatially locating the IOL focal point and in measuring the focal length in a broad range of both positive and negative powers including high-magnification IOLs with power greater than +/-20 D. We have tested various IOL samples with both positive (+5 to +30 D) and negative (-5 to -20 D) powers and we have obtained high levels of power testing repeatability estimated by a SD in the interval of 0.004-0.06/0.003-0.013 D and a relative error in the interval of 0.015-0.3/0.02-0.16%, for positive/negative IOLs, respectively. CONCLUSIONS: The presented IOL power testing method offers a simple, accurate, objective, quick, and relatively inexpensive approach for dioptric power measurement of positive and negative IOLs. It provides an independent source of IOL power measurement data and information for evaluating the effectiveness and safety of novel IOL products.

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Remote image based retinopathy of prematurity diagnosis: a receiver operating characteristic analysis of accuracy.

BACKGROUND/AIMS: Telemedicine offers potential to improve the accessibility and quality of diagnosis of retinopathy of prematurity (ROP). The aim of this study was to measure accuracy of remote image based ROP diagnosis by three readers using receiver operating characteristic (ROC) analysis. METHODS: 64 hospitalised infants who met ROP examination criteria underwent two consecutive bedside procedures: dilated examination by an experienced paediatric ophthalmologist and digital retinal imaging with a commercially available wide angle camera. 410 images from 163 eyes were reviewed independently by three trained ophthalmologist readers, who classified each eye into one of four categories: no ROP, mild ROP, type 2 prethreshold ROP, or ROP requiring treatment. Sensitivity and specificity for detection of mild or worse ROP, type 2 prethreshold or worse ROP, and ROP requiring treatment were determined, compared to a reference standard of dilated ophthalmoscopy. ROC curves were generated by calculating values for each reader at three diagnostic cut-off levels: mild or worse ROP (that is, reader was asked whether image sets represented mild or worse ROP), type 2 prethreshold or worse ROP (that is, reader was asked whether image sets represented type 2 prethreshold or worse ROP), and ROP requiring treatment. RESULTS: Areas under ROC curves ranged from 0.747-0.896 for detection of mild or worse ROP, 0.905-0.946 for detection of type 2 prethreshold or worse ROP, and 0.941-0.968 for detection of ROP requiring treatment. CONCLUSIONS: Remote interpretation is highly accurate among multiple readers for the detection of ROP requiring treatment, but less so for detection of mild or worse ROP.

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[Diagnosis of diplopia].

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Diagnostic Techniques, Ophthalmological↗