PubMed · 16732226
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P Yesudian. 2006-05-27. An amicable divorce?. https://doi.org/10.1038/sj.bdj.4813666
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BACKGROUND: From 2003 to 2005, the European Union supported the EQUAL-initiative to develop methodological external quality assessment (EQA) schemes for genotyping (EQUALqual), quantitative PCR (EQUALquant), and sequencing (EQUALseq). As a relevant part of the EQUALseq program, a training course was held subsequent to the first EQA Program (EQAP1). The success of this course was reassessed in a 2nd EQUALseq round (EQAP2). METHODS: In September 2005, a 3-day training course took place. We invited 8 laboratories with below-average performance in EQAP1 to improve their methodological and analytical/proficiency skills by lectures and practical work. To compare the results of the pretraining and posttraining EQUALseq rounds, we distributed 2 samples used in the first EQUAL round, but this time we provided different oligonucleotide sets. We evaluated the results by means of a previously described scoring system. RESULTS: In EQAP2, 6 laboratories returned complete data sets, corresponding to an overall 14% of the 43 laboratories that had finished EQAP1. The scoring results for samples A (P=0.0025) and B (P=0.0125) demonstrated a significant improvement in EQAP2. Overall, a substantial improvement of technical and interpretative skills was demonstrated (P=0.0051). In general, the workshop experience was highly rated by the participants. CONCLUSIONS: Methodologic EQAPs in DNA sequencing are appropriate tools to uncover strengths and weaknesses in both technique and proficiency, emphasizing the need for mandatory EQAPs. Training courses, together with 2nd-round reiterations, should be implemented into methodological EQAPs in molecular diagnostics to improve technical performance and proficiency in genetic testing.
INTRODUCTION: The number of health-related homepages is increasing and their content is exceeding. The visitor, let him/her be a private visitor or an expert, a patient or relative would like to access relevant data, trust the accuracy and up-to-date state of the web content. It is in the nature of these kind of services, that visitors would share their question and remarks with the authors specialized in a particular topic. Among others these circumstances led to the format and content-related regulation of websites. OBJECTIVE: In a nationwide research the authors examined, to what extent the Hungarian sites meet the requirements of the Health on Net codification and the criteria of the European Union Committee. METHOD: By studying the quality criteria-related websites, the authors examined each Hungarian website to see how the Hungarian pages live up to the regulations. The work concentrates on the content, but it does not neglect functional analysis either. CONCLUSION: The authors conclude, that in spite of shortcomings, home webpages aim to keep the directives of the European Union.