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Anorectal dysfunction in multiple sclerosis.

E Munteis·M Andreu·M J Téllez·D Mon·A Ois·J Roquer
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Abstract

OBJECTIVE: To ascertain the prevalence of anorectal dysfunction (ARD) in patients with multiple sclerosis (MS) and its relationship with MS clinical characteristics. METHODS: Prospective transversal study in 193 patients with MS. All patients fulfilled a protocol that included: demographic variables, clinical characteristics of MS and the presence of ARD and urinary dysfunction (UD). RESULTS: One hundred and ninety-three patients: 66.8% women, an average age of 42.8 (12.1) years; 67.8% of patients had relapsing remitting MS, 21.2% a secondary progressive and 10.9% a primary progressive form. The average duration of MS was 10.7 (9.4) years and the EDSS 2.8 (2.3). ARD was present in 93 patients (48.2%), and UD in 50.2%. ARD associated to UD was present in 35.7% of cases. The univariate study revealed that patients with ARD were older (P <0.001), had greater disability (P <0.0001), longer disease duration (P <0.001) and a greater association with UD (P<0.0001). ARD was more frequent in progressive forms (P<0.0001). The logistic regression analysis showed that female sex (P = 0.015), EDSS (P = 0.002) and UD (P = 0.003) were independent factors related to ARD. CONCLUSION: ARD is a highly prevalent disorder in MS. Female sex, EDSS and UD are independent predictors of ARD development.

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AdultAge FactorsAge of OnsetAnal CanalAnalysis of VariancePersons with DisabilitiesDisease ProgressionFemaleHumansMaleMiddle AgedMultiple SclerosisMultivariate AnalysisPrevalenceProspective StudiesRectumJournal Article

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E Munteis, M Andreu, M J Téllez, D Mon, A Ois, J Roquer. 2006. Anorectal dysfunction in multiple sclerosis.. https://doi.org/10.1191/135248506ms1254oa

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