PubMed · 16609183
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S S Hasnain, J R Helliwell, H Kamitsubo. 2000-05-01. SR source to science.. https://doi.org/10.1107/s0909049500004404
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Precision oncology relies on integrating tumour fraction, variant allele frequency, clonal haematopoiesis of indeterminate potential assessment, pathogenicity, and clinical context into next-generation sequencing interpretation, enabling biologically informed and clinically meaningful treatment decisions while reducing the risk of overinterpreting nontumour or nonactionable genomic alterations.