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PubMed · 16595178

Mining the oocyte transcriptome.

Claudia Andreu-Vieyra·Yi-Nan Lin·Martin M Matzuk
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Abstract

Mammalian folliculogenesis and oocyte physiology are complex and not fully understood. However, major advances over the past 15 years in our ability to create and study in vivo models have improved our understanding of these essential physiological processes. More recently, the availability of vast arrays of DNA sequence information in the forms of "complete" genomes, expressed sequence tag libraries and microarray data from reproductive tissues have stimulated the discovery of new information through genome scanning, prediction programs and in silico screening techniques. These technological improvements will help to expand our understanding of folliculogenesis and oocyte physiology and improve human reproductive health.

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Bone Morphogenetic Protein 15Cell CommunicationConnexinsFemaleGene Expression RegulationGranulosa CellsGrowth Differentiation Factor 9HumansIntercellular Signaling Peptides and ProteinsMeiosisOligonucleotide Array Sequence AnalysisOocytesOvarian FollicleRNA InterferenceRNA, MessengerTranscription, GeneticJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tReview

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Claudia Andreu-Vieyra, Yi-Nan Lin, Martin M Matzuk. 2006-04-03. Mining the oocyte transcriptome.. https://doi.org/10.1016/j.tem.2006.03.010

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