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PubMed · 16311106

Osteosarcoma: basic science and clinical implications.

James B Hayden·Bang H Hoang
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Abstract

Current therapy for osteosarcoma successfully treats 60% to 70% of patients. Attempts to identify patients who will respond poorly to therapy has focused on the use of new biologic markers or microarray cluster analysis. New potential therapeutic targets, including growth factors, chemokines, transcription factors, and angiogenic factors, are being evaluated for their roles in osteosarcoma. These new targets may provide mechanisms to treat the patients who would respond poorly to standard therapy.

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Age FactorsAgedBone NeoplasmsChemotherapy, AdjuvantCombined Modality TherapyFemaleGenetic Predisposition to DiseaseHumansMaleMiddle AgedMolecular BiologyNeoplasm StagingOsteosarcomaPrognosisRadiotherapy, AdjuvantRisk AssessmentSex FactorsSurvival AnalysisComparative StudyJournal ArticleReview

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James B Hayden, Bang H Hoang. 2006. Osteosarcoma: basic science and clinical implications.. https://doi.org/10.1016/j.ocl.2005.06.004

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