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PubMed · 15921017

Multiple myeloma.

Tracy B White·Donna Caldwell·Jeannean Hall-Rollins
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Abstract

OBJECTIVES: After completing this article, readers should be able to: Recognize the signs and symptoms of multiple myeloma. Discuss the process used to confirm a multiple myeloma diagnosis. Identify imaging modalities used to diagnose the disease. Describe the appearance of multiple myeloma on radiographic images. Explain the use of computed tomography, magnetic resonance and positron emission tomography in imaging of multiple myeloma. List traditional and newer multiple myeloma treatment options.

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Bence Jones ProteinDiagnostic ImagingHumansMultiple MyelomaNeoplasm StagingPrognosisRisk FactorsJournal ArticleReview

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Tracy B White, Donna Caldwell, Jeannean Hall-Rollins. Multiple myeloma.. https://pubmed.ncbi.nlm.nih.gov/15921017/

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Plasma cell leukemia with pleomorphic plasma cells--a case report.

A case of plasma cell leukemia showing mostly pleomorphic plasma cells in the form of convoluted and multilobated nuclei with some having bilobed nuclei and internuclear bridges is being reported for its rarity of occurrence. Patient presented with congestive cardiac failure and features of nephropathy. There were no lytic lesions in the bone. Serum electrophoresis did not show any M-band while urine electrophoresis demonstrated Bence Jones protein confirming a light chain only type of myeloma. Patient is in remission 5 months after diagnosis. The significance of recognising such pleomorphic plasma cells is discussed.

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