PubMed · 1589642
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H Otsuka. 1992. [Chronic hyperventilation].. https://pubmed.ncbi.nlm.nih.gov/1589642/
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Clonic and tonic seizure-like movements of the extremities were observed during induction of anaesthesia with sevoflurane in a 9-yr-old girl. The tonic movements were associated with respiratory alkalosis and were not abolished by an i.v. injection of thiamylal 75 mg. Arterial pressure, heart rate and body temperature remained normal during the episode. Ventilation was assisted easily and then controlled via a face mask. No neurological abnormalities were obvious after the anaesthesia. The movements may have been the result of seizure activity in the central nervous system, or myoclonus of the extremities.
Mechanical ventilation of chronic obstructive pulmonary disease (COPD) patients with acute respiratory failure poses certain problems specific to the pathophysiology of this condition. These difficulties arise during the mechanical ventilation phase as well as during weaning. A thorough knowledge of the mechanisms involved and of the means of minimizing complications allows the vast majority of these patients to be weaned successfully. This article reviews some of these problems and possible solutions.
A 56-year-old man with a longstanding tracheostomy presented to the hospital with upper GI bleeding and was found to have a profound respiratory alkalosis. The cause of this patient's involuntary hyperventilation was hiccuping complicated by the absence of glottic closure.