General perspectives, pathogenesis, pathophysiology, and skeletal dysfunction.

F J Frassica; F H Sim

doi:10.3928/0147-7447-19920501-12

Home/Archive/PubMed

PubMed · 1589352

General perspectives, pathogenesis, pathophysiology, and skeletal dysfunction.

F J Frassica·F H Sim

View original source ↗Export metadata ↓

Abstract

A better understanding of the pathogenesis and pathophysiology of the metastatic process is leading to improvements in diagnosis and treatment. Evaluation of specific areas of disorder of skeletal function, including hematopoiesis, mineral metabolism, and structural support, is important. Continued developments are necessary to minimize or prevent effects on the skeleton related to the metastatic process.

Explore related subjects

Biomechanical Phenomena Bone Neoplasms Bone and Bones Diagnosis, Differential Hematopoiesis Humans Minerals Neoplasm Metastasis Journal Article

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

F J Frassica, F H Sim. 1992. General perspectives, pathogenesis, pathophysiology, and skeletal dysfunction.. https://doi.org/10.3928/0147-7447-19920501-12

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1998

Perspectives: some roles of mechanical usage, muscle strength, and the mechanostat in skeletal physiology, disease, and research.

Explore the source record for details and available documents.

Biomechanical Phenomena↗

PubMed1998

Implant screw mechanics.

Osseointegrated implant support of dental restorations continues to be a popular option for the contemporary patient with missing natural dentition. This article focuses on the two most frequently used methods for attaching final prostheses to endosseous implants. The authors offer practical solutions for minimizing implant screw loosening and describe the factors involved in maintaining stable screw joint assembly.

Biomechanical Phenomena↗

PubMed1997

Absence of a barrier to backwards rotation of the bacterial flagellar motor demonstrated with optical tweezers.

A cell of the bacterium Escherichia coli was tethered covalently to a glass coverslip by a single flagellum, and its rotation was stopped by using optical tweezers. The tweezers acted directly on the cell body or indirectly, via a trapped polystyrene bead. The torque generated by the flagellar motor was determined by measuring the displacement of the laser beam on a quadrant photodiode. The coverslip was mounted on a computer-controlled piezo-electric stage that moved the tether point in a circle around the center of the trap so that the speed of rotation of the motor could be varied. The motor generated approximately 4500 pN nm of torque at all angles, regardless of whether it was stalled, allowed to rotate very slowly forwards, or driven very slowly backwards. This argues against models of motor function in which rotation is tightly coupled to proton transit and back-transport of protons is severely limited.

Biomechanical Phenomena↗