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PubMed · 15802288

GandrKB--ontological microarray annotation and visualization.

Daniel Schober·Ulf Leser·Martin Zenke·Jens Reich
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Abstract

SUMMARY: The Gandr (gene annotation data representation) knowledgebase is an ontological framework for laboratory-specific gene annotation. Gandr uses Protege 2000 for editing, querying and visualizing microarray data and annotations. Genes can be annotated with provided, newly created or imported ontological concepts. Annotated genes can inherit assigned concept properties and can be related to each other. The resulting knowledgebase can be visualized as interactive network of nodes and edges representing genes and their functional relationships. This allows for immediate and associative gene context exploration. Ontological query techniques allow for powerful data access.

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AlgorithmsComputer GraphicsDocumentationGene Expression ProfilingGene Expression RegulationModels, BiologicalOligonucleotide Array Sequence AnalysisPhylogenySignal TransductionSoftwareUser-Computer InterfaceJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.

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Daniel Schober, Ulf Leser, Martin Zenke, Jens Reich. 2005-03-31. GandrKB--ontological microarray annotation and visualization.. https://doi.org/10.1093/bioinformatics%2Fbti401

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