PubMed · 15798853
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C E Coimbra. 2005-03-22. [Not Available].. https://doi.org/10.1590/s0102-311x1991000400001
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Precision oncology relies on integrating tumour fraction, variant allele frequency, clonal haematopoiesis of indeterminate potential assessment, pathogenicity, and clinical context into next-generation sequencing interpretation, enabling biologically informed and clinically meaningful treatment decisions while reducing the risk of overinterpreting nontumour or nonactionable genomic alterations.