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PubMed · 15756311

Combinatorial libraries - from solution to 2D microarrays.

Juan José Díaz-Mochón·Laurent Bialy·Lise Keinicke·Mark Bradley
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Abstract

Enzymatic modifications of split and mix libraries were followed by "pulling down" onto a 2-dimensional DNA microarray, via PNA tagging; this allowed complete library interrogation of all members of the split and mix library.

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Combinatorial Chemistry TechniquesMolecular StructureOligonucleotide Array Sequence AnalysisPeptide HydrolasesPeptide Nucleic AcidsProto-Oncogene Proteins c-ablSolutionsJournal ArticleResearch Support, Non-U.S. Gov't

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Juan José Díaz-Mochón, Laurent Bialy, Lise Keinicke, Mark Bradley. 2005-01-17. Combinatorial libraries - from solution to 2D microarrays.. https://doi.org/10.1039/b415847d

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