[Angioedema].

Abstract

Angioedema, deep mucocutaneous swelling, usually develops around the eyes and lips but may also affect the hands, feet, and throat. Allergic reactions to medications or foods can cause acute angioedema. Hereditary angioedema is a rare disorder, which is related to low levels or abnormal functioning of C1 inhibitors. Acquired C1 inhibitor deficiency is most frequently associated with B-cell lymphoproliferative disease. Some drugs including angiotensin-converting enzyme inhibitors can cause angioedema. Environmental elements such as pressure on the skin and exercise also can result in angioedema in some individuals. In addition, angioedema sometimes may occur in serum sickness, immune system disorders, or may be associated with eosinophilia.