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PubMed · 15514803

Sensitivity increase in molecular recognition by decrease of the sensing particle size and by increase of the receptor binding site--a case with chemomechanical polymers.

Hans-Jörg Schneider·Liu Tianjun·Nino Lomadze
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Abstract

For the first time it is shown that diminishing the particle size of a chemomechanical polymer leads to a dramatic sensitivity increase, with a large response triggered e.g. by action of external AMP; as illustrated with carbohydrate model complexes in solution, the necessary high binding affinity can be achieved by providing an excess of recognition units in one of the partners.

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Binding SitesCarbohydratesMolecular ConformationParticle SizePolymersSensitivity and SpecificityJournal Article

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Hans-Jörg Schneider, Liu Tianjun, Nino Lomadze. 2004-09-24. Sensitivity increase in molecular recognition by decrease of the sensing particle size and by increase of the receptor binding site--a case with chemomechanical polymers.. https://doi.org/10.1039/b409331c

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