RNA conformational classes.

Bohdan Schneider; Zdenek Morávek; Helen M Berman

doi:10.1093/nar/gkh333

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PubMed · 15016910

RNA conformational classes.

Bohdan Schneider·Zdenek Morávek·Helen M Berman

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Abstract

RNA exhibits a large diversity of conformations. Three thousand nucleotides of 23S and 5S ribosomal RNA from a structure of the large ribosomal subunit were analyzed in order to classify their conformations. Fourier averaging of the six 3D distributions of torsion angles and analyses of the resulting pseudo electron maps, followed by clustering of the preferred combinations of torsion angles were performed on this dataset. Eighteen non-A-type conformations and 14 A-RNA related conformations were discovered and their torsion angles were determined; their Cartesian coordinates are available.

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Models, Molecular Molecular Structure Nucleic Acid Conformation RNA, Ribosomal RNA, Ribosomal, 23S RNA, Ribosomal, 5S Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

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Bohdan Schneider, Zdenek Morávek, Helen M Berman. 2004-03-11. RNA conformational classes.. https://doi.org/10.1093/nar%2Fgkh333

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