Intentional seizure interruption may decrease the seizure frequency in drug-resistant temporal lobe epilepsy.

J Janszky; A Szücs; G Rasonyi; R Schulz; M Hoppe; A Hollo; G Barcs; A Kelemen; P Halasz; A Ebner

doi:10.1016/s1059-1311(03)00162-6

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PubMed · 15010052

Intentional seizure interruption may decrease the seizure frequency in drug-resistant temporal lobe epilepsy.

J Janszky·A Szücs·G Rasonyi·R Schulz·M Hoppe·A Hollo·G Barcs·A Kelemen·P Halasz·A Ebner

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Abstract

We investigated the nature of preictal subjective phenomena and whether they had any effect on the seizure frequency in 95 adult patients with medial temporal lobe epilepsy. Seventy-three (77%) patients indicated that they experienced seizure-provoking factors. Ten patients (11%) had prodromas independent of auras, while auras occurred in 89%. Forty-four patients (46%) reported that that they had tried to stop their seizures in the presence of prodroma or aura and this action had resulted in success at least once. Twenty-one patients (22%) regularly tried to stop their seizures because this effort was often successful according to their interpretation. Patients who reported that they could frequently inhibit their seizures had 1.8 +/- 1.6 seizures/month, a significantly lower mean seizure frequency than those 74 patients who did not do it regularly (4.6 +/- 4.8 seizures/month, P<0.001). Patients who reported regular experience in inhibiting intentionally their seizures more often had affective (P=0.05) and vertiginous auras (P<0.01) as well as isolated auras (P<0.05). Patients who experienced provoking factors showed the same seizure frequency as those who did not. Our results suggest that intentional seizure inhibition had an impact on the severity of drug-resistant epilepsy.

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Adolescent Adult Anticonvulsants Chi-Square Distribution Epilepsy, Temporal Lobe Female Humans Male Middle Aged Retrospective Studies Seizures Comparative Study Journal Article

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J Janszky, A Szücs, G Rasonyi, R Schulz, M Hoppe, A Hollo, G Barcs, A Kelemen, P Halasz, A Ebner. 2004. Intentional seizure interruption may decrease the seizure frequency in drug-resistant temporal lobe epilepsy.. https://doi.org/10.1016/s1059-1311(03)00162-6

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