PubMed · 14943294
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G E BURCH. 1952. Vectorcardiography.. https://doi.org/10.1001/archinte.1952.00240080003001
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Prenatal growth deficiencies as well as gender have been associated with cardiovascular disease in later life. It is also known that the duration of fetal cardiac time intervals (CTI) are dependent on fetal development. The aim of this work was to examine the relationship between fetal CTI in healthy and intrauterine growth retardation (IUGR) fetuses, taking gender into account. A total of 269 magnetocardiograms (MCG) were obtained in 47 healthy and 27 IUGR pregnancies. In each signal-averaged MCG, durations of CTI were determined. Age- and heart rate-corrected values were compared between normal and IUGR fetuses separately with respect to gender. Overall, there was an association between atrial and ventricular conduction times and estimated fetal body weight. In female fetuses, IUGR was associated with shorter P WAVE, PQ segment, PR interval, and QRS complex and longer STT and QT intervals. For males, this was so only for P wave, QRS complex, and STT interval. The shortening of conduction times in IUGR may be explained by reduced cardiac muscle mass associated with lower body weight. On the other hand, the gender-specific differences, particularly in the IUGR fetuses may be due to hormonal factors.
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The electrocardiogram (ECG) is a representative signal containing useful information about the condition of the heart. The shape and size of the P-QRS-T wave, the r-r interval, etc., may help to identify the nature of disease afflicting the heart. However, human observer cannot directly monitor these subtle details and it is difficult to evaluate the cardiac health using ECG alone. Hence, the fusion of ECG, blood pressure, saturated oxygen content and respiratory data for achieving improved clinical diagnosis of patients in cardiac care units. In this study, a computer based analysis and display of the heterogeneous signals for the detection of life threatening states is demonstrated using fuzzy logic based data fusion. And to evaluate the severity of the disease a new parameter, deterioration index is proposed and results are tabulated for various cases.