PubMed · 1493011
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N Balkrishna. 1992. Endocervical sampling devices.. https://pubmed.ncbi.nlm.nih.gov/1493011/
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Cervical smears should contain endocervical cells to be accepted as representative for a cytologic diagnosis. In this prospective study with 200 women we compared cytologic specimens obtained by Cervex-Brush (100 women) or by conventional cotton-swab (100 women) technique. The incidence of smears containing cylindrical and metaplastic cells was 85% in the Cervex-Brush group and only 58% in the cotton-swab group. We believe that the application of the Cervex-Brush or a similar instrument should result in fewer repeat smears and fewer false-negative smears and thus in an improvement of the cervical cytology.
Prenatal diagnoses were performed on six selected pairs of parents known to be carriers of Hb mutations by testing transcervical cells (TCCs) retrieved, prior to chorionic villus sampling (CVS), by aspiration of the cervical mucus from the pregnant mothers at 10-12 weeks of gestation. A concordance between the results of testing chorionic villus cells and isolated clumps of trophoblastic cellular elements was observed in four of the six cases.