PubMed · 14907169
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J J FLANAGAN. 1952. Bronchoscopic technique.. https://doi.org/10.1007/bf02959389
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Screening studies involving chest x-rays with and without additional sputum cytology, have failed to bring about any reduction in mortality from lung cancer. With regard to all other potential screening methods, no studies investigating tumor-specific mortality are available. Against such a background, none of the relevant societies recommend systematic screening. Sputum cytology is sensitive only for central lesions. Autofluorescence bronchoscopy is limited to the detection of early malignant and premalignant lesions in the central airways. While CT screening detects numerous round foci, only a few of these prove to be carcinomas. In contrast to these findings, we have the positive results of non-controlled screening studies employing low-dose CT, which, however, has not been widely accepted.
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Subglottic cysts are associated with prematurity and periods of early neonatal intubation and are a rare cause of infant stridor. In this study we analyse our experience of this rare but important problem. We discuss the aetiology, diagnosis and management of subglottic cysts. We carried out a retrospective review of all cases of subglottic cysts presenting to the otorhinolaryngology department at the Leeds teaching hospitals trust during the period between 1995 and 2005. In total seven patients were identified. A retrospective review of the case notes of all patients proven to have subglottic cysts at direct laryngoscopy and bronchoscopy was undertaken. Seven patients were identified, four males and three females. Five were born premature (24-31 weeks). All were intubated with average intubation period of 20.6 days. Six of our patients' underwent endoscopic marsupialisation using cup forceps and one with a contact diode laser. Two patients had recurrence of the cyst and had a repeat of endoscopic marsupialisation. This study highlights the associated risk of neonatal intubation with the risk of formation of subglottic cysts, and the need for early diagnosis and appropriate treatment to avoid unnecessary morbidity.