PubMed · 14894639
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C STONE. 1952. Aftercare.. https://pubmed.ncbi.nlm.nih.gov/14894639/
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PURPOSE: To review the effectiveness of routine visits and routine tests in detecting isolated locoregional recurrences in asymptomatic patients after treatment for early-stage invasive breast cancer. METHODS: Systematic review and meta-analysis. The proportion of isolated locoregional recurrences diagnosed during routine visits or routine tests in asymptomatic patients was compared with the proportion of isolated locoregional recurrences in symptomatic patients. RESULTS: Twelve studies that involved a total of 5,045 patients and 378 isolated locoregional recurrences were identified. Pooling data showed an overall estimate of 40% of isolated locoregional recurrences diagnosed during routine visits or routine tests in asymptomatic patients (95% CI, 35 to 45). Of these, 47% (95% CI, 39 to 54) were diagnosed after mastectomy, and 36% (95% CI, 28 to 43) were diagnosed after breast-conserving therapy (relative risk, 1.327; 95% CI, 1.014 to 1.738). Apart from differences in therapy, we have not been able to discern subgroups of patients for whom results were different. CONCLUSION: Approximately 40% of isolated locoregional recurrences are diagnosed during routine visits and routine tests in asymptomatic patients treated for early-stage invasive breast cancer. We could not assess whether these were detected by either physical examination or other tests, nor if the detection of asymptomatic isolated recurrences had any influence on potential for cure or quality of life. As the overall quality of the included studies and the overall incidence of isolated locoregional recurrences are low, this systematic review highlights the need for prospective comparative studies on cost-effective strategies for the follow-up of patients after a diagnosis of breast cancer.
Delayed discharge fines increase pressure on trusts to prevent delays. The loss of vital information between health and social services undermines discharges' credibility. Pooled budgets between the two sectors are a powerful means of fostering innovation.
The large number of post-transplantation patients overwhelm the capacity of most transplantation centers (TC) to provide aftercare, with the result that close cooperation has been established between transplantation centers and ambulatory centers. Surveillance of immunosuppression, but also the treatment of concomitant cardiovascular diseases and the elevated tumorigenesis rate in transplanted patients, presuppose a high degree of readiness to undergo further education on a permanent basis. Furthermore, patient compliance is a factor of decisive importance for ensuring optimal care by the general physician. In close cooperation with the TC, the latter bears a considerable burden of responsibility for the lifelong aftercare of such patients.