Two brains, one clock.

Carlo A Marzi

doi:10.1016/j.tics.2003.10.015

Home/Archive/PubMed

PubMed · 14697394

Two brains, one clock.

Carlo A Marzi

View original source ↗Export metadata ↓

Abstract

A recent study has shown that information about the duration of brief time intervals acquired by one side of the brain is readily available to the other cerebral hemisphere in a patient in which the corpus callosum and the other forebrain commissures have been sectioned. This strongly suggests that the internal clock that measures time duration is subcortical, and that its output can be easily projected to both hemispheres via subcortical commissures.

Explore related subjects

Attention Brain Mapping Cerebral Cortex Corpus Callosum Dominance, Cerebral Humans Neural Pathways Prosencephalon Time Perception Journal Article

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

Carlo A Marzi. 2004. Two brains, one clock.. https://doi.org/10.1016/j.tics.2003.10.015

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2004

Target evaluation processing and serum levels of nerve tissue protein S100B in patients with remitted major depression.

Selective attention processes (N2 and P3 components of event-related potentials (ERPs)) have been shown to be impaired in depressed patients but findings have been mixed. Part of this variability might be explained by neurobiological factors. ERPs (Go/Nogo paradigm) were investigated in patients with remitted major depression in relation to S100B. S100B, an astroglial protein with neuroplastic properties, has been shown to be increased in depression. Its pathophysiologic role in depression, however, is not yet sufficiently understood. Patients with increased S100B serum levels (n=6) showed a normal N2- and P3-amplitude in contrast to a reduced N2- and P3-amplitude in patients with normal S100B serum levels (n=6). These findings provide evidence of a correlation between S100B levels and attentional processes in patients with recurrent depression and further substantiate S100B's role as a marker in the course of affective disorders.

Attention↗

PubMed2004

Neuropsychological performance in obsessive-compulsive disorder: a critical review.

There is growing evidence for neuropsychological dysfunction in obsessive-compulsive disorder (OCD) related to an underlying frontal lobe and/or basal ganglia dysfunction. The following paper is a systematical review of the existing literature on cognitive impairment in OCD patients. Fifty studies were surveyed with regard to methodological aspects and cognitive impairments found in OCD patients. In addition, the impact of confounding variables such as psychotropic medication, co-morbidity or severity of symptoms on neuropsychological functioning as well as effects of treatment are discussed. OCD is often related to memory dysfunction that seems to be associated with impaired organization of information at the stage of encoding. Several other executive functions are also commonly disturbed, though results are inconsistent. The results of our study suggest that some cognitive deficits seem to be common in OCD, but future studies should focus more on possible confounding variables such as co-morbidity or psychotropic medication.

Attention↗

PubMed2004

Infants chunk object arrays into sets of individuals.

Research suggests that, using representations from object-based attention, infants can represent only 3 individuals at a time. For example, infants successfully represent 1, 2, or 3 hidden objects, but fail with 4 (Developmental Science 6 (2003) 568), and a similar limit is seen in adults' tracking of multiple objects (see Cognitive Psychology 38 (1999) 259). In the present experiments we used a manual search procedure to ask whether infants can overcome this limit of 3 by chunking individuals into sets. Experiments 1 and 2 replicate infants' failure to represent a total of 4 objects. We then show that infants can exceed this limit when items are spatiotemporally grouped into two sets of 2 prior to hiding, leading infants to successfully represent a total of 4 objects. Experiment 3 demonstrates that infants tracked the 4 objects as two sets of 2, searching for each set in its correct hiding location. That infants represented the number of individuals in each set is demonstrated by their reaching for the correct number of objects in each location. These results suggest that by binding individuals into sets, infants can increase their representational capacity. This is the first evidence for chunking abilities in infants.

Attention↗