Search PubMed⌕ Search

PubMed · 14633421

Problems with the concept 'interpretation'.

Abstract

Consensus on the conceptualisation of 'interpretation', the most characteristic feature of psychoanalytic technique, has proven elusive. Attempts at precising the meaning of this term are reviewed. The role of intuition and suggestion in interpretation are commented upon. There seem to exist polarities in interpreting styles. It is the author's contention that these are mostly contingent on the practitioner's adscription to the topographical or the structural model of the mind. The tendency to interpret deeply unconscious elements would correspond to pre-structural technique, whereas the tendency to direct the patient's attention to preconscious manifestations would be characteristic of the structural orientation. Clinical material is provided to illustrate the divergence of underlying theories of technique. The topographical interpreting of Freud and his early followers is different from the interpreting used in contemporary structural technique. 'Deep' interpreting approaches continue to be used side by side with clarification-like interpretations. The reasons for this coexistence are examined. There are powerful motivations for the adherence to pre-structural interpreting. It seems to gratify the analysand's dependency wishes and the analyst's narcissism more directly. It also provides a less sublimated satisfaction of epistemophilic drives. Maintaining ill-defined the concept 'interpretation' facilitates the application of the topographical technique with its irrational gratifications.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Cecilio Paniagua. 2003. Problems with the concept 'interpretation'.. https://doi.org/10.1516/00207570360720371

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Global Genomic Surveillance.

Global genomic surveillance has emerged as a foundational pillar of public health in the twenty-first century, enabling real-time tracking of pathogen evolution and informing outbreak response. This chapter examines the strategic architecture of global genomic surveillance, focusing on its application to arboviruses such as chikungunya virus (CHIKV). It explores the integration of genomic data with epidemiological, clinical, and environmental information within a One Health framework, while addressing critical challenges in governance, equity, and interoperability. The discussion covers the entire genomic surveillance workflow, from sample collection and sequencing to bioinformatic analysis and phylogenetic inference, and highlights the transformative role of artificial intelligence (AI) in predictive surveillance. By analyzing global initiatives, operational barriers, and emerging technologies, this chapter underscores the necessity of sustainable, equitable, and interoperable genomic systems to proactively address current and future infectious disease threats.

Humans↗

Systematic Dissection of Key Driver Perturbation Signatures in Single Cells via ECCITE-seq.

CRISPR screens, such as expanded CRISPR-compatible cellular indexing of transcriptomes and epitopes by sequencing (ECCITE-seq), enable the simultaneous measurement of transcriptomes, gRNA identity, and cell-surface protein expression at single-cell resolution to systematically interrogate gene function. This platform provides a powerful and scalable experimental approach for validating disease-associated regulators identified by large-scale association studies and other computational methods, including network-based analyses of multi-omics data. Here, as an example application, we describe an ECCITE-seq framework to characterize the transcriptomic consequences of perturbing multiple neuronal key driver genes associated with Alzheimer's disease (AD) in human-induced pluripotent stem cell (hiPSC)-derived neurons. More broadly, by integrating customized pooled gRNA libraries with different CRISPR effectors across multiple cell types, this approach allows for the assessment of the regulatory impact of candidate genes implicated in development and disease processes.

Humans↗

Identification of Genome-Wide Chromatin Structural Aberration in Cancer by Hi-C Analysis.

Aberrant three-dimensional genome organization is a hallmark of cancer, often driving oncogene activation through mechanisms such as enhancer hijacking. High-throughput chromosome conformation capture (Hi-C) maps these interactions on a genome-wide scale. Unlike earlier dilution-based methods, in situ Hi-C performs proximity ligation within intact nuclei, minimizing random ligation noise and enabling fine-scale structure detection. This chapter describes an optimized in situ Hi-C protocol tailored for cancer cell lines using MboI digestion and biotin-mediated pull-down to generate high-complexity libraries. We further outline a computational workflow that extends beyond standard topological mapping of compartments and topologically associating domains to identify cancer-specific aberrations. Specifically, we focus on detecting chromosomal rearrangements (structural variants) and characterizing the distinct circular topology of extrachromosomal DNA. This integrated experimental and analytical framework provides the necessary tools to dissect the spatial dysregulation underlying tumor evolution.

Humans↗