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PubMed · 14601526

Technology evaluation: CpG-7909, Coley.

Stéphane Paul
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Abstract

Coley Pharmaceutical (formerly CpG ImmunoPharmaceuticals) is developing CpG-7909 (ProMune) for use in the potential treatment of cancer and as a vaccine adjuvant. By April 2000, CpG-7909 had entered phase I/II trials for cancer and in March 2002, Coley initiated a phase I trial in non-Hodgkin's lymphoma in combination with rituximab (Rituxan). By October 2002, CpG-7909 was in phase II trials as a vaccine adjuvant. Cpg-7909 is currently also undergoing phase II trials for melanoma.

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Adjuvants, ImmunologicAnimalsAntineoplastic AgentsClinical Trials, Phase I as TopicClinical Trials, Phase II as TopicCpG IslandsDNA-Binding ProteinsHepatitis BHumansNeoplasmsOligodeoxyribonucleotidesOligodeoxyribonucleotides, AntisenseReceptors, Cell SurfaceToll-Like Receptor 9Clinical TrialControlled Clinical TrialEvaluation StudyJournal Article

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Stéphane Paul. 2003. Technology evaluation: CpG-7909, Coley.. https://pubmed.ncbi.nlm.nih.gov/14601526/

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