PubMed · 14123144
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A LISTER. 1963. FLAT CHAMBER.. https://pubmed.ncbi.nlm.nih.gov/14123144/
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PURPOSE: To evaluate the influence of peripheral 360 degrees retinal cryocoagulation on the blood-aqueous barrier of patients with retinal vascular disorders. METHODS: The aqueous of 50 eyes of 50 patients with diabetic retinopathy or central vein occlusion was measured by laser flare photometry (FC-2000, Kowa) before peripheral 360 degrees retinal cryocoagulation and 1 day, 1 week, and 1 month thereafter. RESULTS: Mean aqueous flare values before treatment were 15.7 (+/-8.2) photon counts/ms; mean cell count was 9.8 (+/-14.8) cells/0.5 mm(3). One day after retinal cryocoagulation flare values had increased statistically significantly to a mean of 39.2 (+/-85.8) photon counts/ms, while the increase in mean cell number to 15.0 (+/-37.2) cells/0.5 mm(3) did not reach statistical significance. One week following treatment, mean flare values had dropped to 30.9 (+/-49.6) photon counts/ms and were no longer significantly elevated compared with baseline, while the mean cell count of 11.1 (+/-27.0) cells/0.5 mm(3) was now statistically significantly elevated compared with baseline. One month after treatment the flare values had decreased to a mean of 19.7 (+/-12.0) photon counts/ms, and mean cell count had decreased to 8.1 (+/-10.4) cells/0.5 mm(3); at this point neither parameter showed a statistically significant difference from baseline values. CONCLUSION: Peripheral 360 degrees retinocryocoagulation does not lead to permanent disturbance of the blood-aqueous barrier.