PubMed · 13771490
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T MIYAKE. 1961-07-20. [Cor pulmonale].. https://pubmed.ncbi.nlm.nih.gov/13771490/
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Lupoid leishmaniasis is a unique form of cutaneous leishmaniasis characterized by unusual clinical features and a chronic relapsing course. Clinically and histologically it is similar to lupus vulgaris, which is thus the most important differential diagnostic consideration. All patients with granulomatous facial lesions coming from endemic areas or with a positive travel history should be suspected of having leishmaniasis. We describe a 59-year-old woman with facial lupoid leishmaniasis.
Cenesthesia is portrayed as a rare differential diagnosis to persistent idiopathic facial pain, including the resulting therapy with antipsychotics. In this case report a female patient developed persistent facial pain 2 years after manifestation of a depressive disorder. The symptoms appeared as a bizarre pain phenomenon closely resembling the psychotic phenomenon of cenesthesia (body hallucinations). Treatment with imipramine and doxepin or a combination of venlafaxin, carbamazepine, and tilidine N had not been successful. Based on diagnostic classification of the complaint as cenesthesia in the context of a depressive disorder, add-on therapy of the atypical antipsychotic ziprasidone was administered. This led to clear improvements in mood and pain symptoms after 4 weeks of treatment.
Chronic muscular skeletal pain syndromes (CMSPS) are one of the major health issues. Despite progress in research, treatment and diagnosis remain difficult. The aim of this study was to examine the influence of somatic dysfunction on CMSPS. A total of 216 patients were examined in a standardized way to assess the influence of morphological and psychosocial factors as well as of somatic dysfunction on CMSPS. Measurements were taken at admission. The results showed a statistically significant link between somatic dysfunction, pain chronicity, pain distribution, and pain-related disability. Since there was no or only a minor correlation between somatic dysfunction and the results of the psychometric testing and the morphological findings, somatic dysfunction should be regarded as an independent factor influencing CMSPS and be further scientifically evaluated.