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PubMed · 1366548

Microbial processes for ascorbic acid biosynthesis: a review.

J Boudrant
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Abstract

L-Ascorbic acid is an important product currently made using the Reichstein process, which is mainly chemical. Recently, bacteria have been identified that are able to transform in a very efficient way glucose to 2,5-keto-D-gluconic acid and this product to 2-keto-L-idonic acid, precursor of L-ascorbic acid. When the corresponding strains are used together, it is possible to get 2-keto-L-idonic acid directly from glucose. Moreover, new strains have been constructed by introducing a gene from a strain responsible for the second step into a strain responsible for the first step. By using one of the new strains, the transformation can be performed in a single step with only one strain. However, the classical process still remains the most competitive.

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AcetobacterAscorbic AcidFermentationModels, BiologicalJournal ArticleReview

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BibTeXRIS

J Boudrant. 1990. Microbial processes for ascorbic acid biosynthesis: a review.. https://doi.org/10.1016/0141-0229(90)90159-n

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