A new method for protein crystallization using high pressure.

K Visuri; E Kaipainen; J Kivimäki; H Niemi; M Leisola; S Palosaari

doi:10.1038/nbt0690-547

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A new method for protein crystallization using high pressure.

K Visuri·E Kaipainen·J Kivimäki·H Niemi·M Leisola·S Palosaari

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Abstract

Crystallization methods for proteins have been the subject of decades of development yet protein crystallization remains the limiting step in structural studies. We present here a new method for protein crystallization--based on the use of high pressure--that enabled us to accelerate dramatically the growth of glucose isomerase crystals. We think this method may have a more general utility.

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Aldose-Ketose Isomerases Carbohydrate Epimerases Crystallization Proteins X-Ray Diffraction Journal Article

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K Visuri, E Kaipainen, J Kivimäki, H Niemi, M Leisola, S Palosaari. 1990. A new method for protein crystallization using high pressure.. https://doi.org/10.1038/nbt0690-547

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