PubMed · 13646176
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L GUBERN SALISACHS, M ROCA BATLLERIA. [Arteritis umbilical].. https://pubmed.ncbi.nlm.nih.gov/13646176/
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INTRODUCTION: Candida arteritis can compromise the functional prognosis of the graft or even the life of the transplant recipient. The infection can be transmitted by the graft. OBSERVATION: A 46 year-old woman contracted a Candida albicans ateritis of the graft following a kidney transplant that led to a detransplantation. The yeast was probably transmitted by the graft from the donor, source of an unknown candida infection: it was found in the conservation liquid of the graft itself, and in the renal artery and vascular pedicle. Analysis of of these three elements by enzymatic electrophoresis showed that they were identical. COMMENTARIES: This case report underlines the need to establish guidelines and sanitary safety measures, notably that of systematically placing in culture the concervation solutions and alerting the transplant team if any fungi are isolated.
Atherogenesis is characterized by a chronic process, which commences years before diabetes mellitus becomes overt. Each step of the pathogenetic cascade is accompanied by inflammation. The degree of inflammation is a key determinant for the process of atherogenesis. C-reactive protein is elevated by inflammatory processes, correlates with the atherosclerotic prognosis and is therefore an important marker of inflammation. It denotes early cardiovascular damages and is elevated in acute coronary syndromes. Cardiovascular risk is excessively elevated in diabetic patients and inflammatory mechanisms are predominant in this group. Preventive interventions and therapeutic strategies based on pathophysiological processes are necessary. The importance of treatment of inflammation increases. Glitazones have been demonstrated to act via antiinflammatory effects. They do not only improve glucose utilisation, but also have pleiotropic effects, which target the increased cardiovascular risks in diabetic patients.
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