PubMed · 13262737
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G AMLANG. 1955-09-30. [Squill therapy].. https://pubmed.ncbi.nlm.nih.gov/13262737/
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The term "mucoactive agent" refers to any medication used to improve the clearance of airway secretions. It is not synonymous with the word "mucolytic" as this strictly means a drug that decreases the viscosity of secretions. In many cases, decreased viscosity will adversely affect cough transport. For this reason many of the older mucolytic agents such as acetylcysteine are not effective for the therapy of lung disease and their use is not recommended. I review here the many classes of mucoactive agents and identify a number of medications with great promise for the treatment of chronic airway disease.
Cigarette smoking can cause a variety of pulmonary and cardiovascular diseases like: bronchitis, emphysema, myocardial infraction as well as lung cancer. The tar phase precipitates in the respiratory tract, inactivating the ciliated epithelium and inhibiting the self-cleaning of bronchia. Herbal remedies increase mucosa secretion and hence facilitate coughing up the secrete residual. The action of expectorant herbs results primarily from their influence on the gastric mucosa and following a reflex stimulation which leads to an increase in secretion of the bronchial glands. Volatile-oil type expectorant herbs have shown a direct stimulatory effect on the bronchial glands by means of local irritation, accompanied with antibacterial and spasmolytic activity. Expectorant herbs containing saponins function reduce the surface tension of the secretions facilitating their separation from the mucous membranes.
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