PubMed · 12980745
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J P MALONE, A M BLAYNEY. 1952. Modified electroconvulsive therapy.. https://doi.org/10.1007/bf02956984
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It is proposed that electroconvulsive therapy (ECT) is not specifically mood-elevating or anti-depressant but that its effect is as an anti-delirium intervention. I suggest that ECT exerts its primary therapeutic effects by inducing a generalized epileptic seizure which operates on the brain like a deep and restorative sleep that acts rapidly to resolve delirium. Provided that the diagnosis is made using sufficiently sensitive criteria, delirium is here assumed to be a common feature of many so-called 'functional' psychoses - frequently occurring as a consequence of sleep deprivation, and leading to symptoms such as hallucinations, bizarre delusions and psychomotor retardation. Testable predictions of this 'anti-delirium' theory of ECT action are described.
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