Diffusion-weighted imaging abnormalities in the splenium after seizures.

Joel Oster; Colin Doherty; P Ellen Grant; Mirela Simon; Andrew J Cole

doi:10.1046/j.1528-1157.2003.40902.x

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Diffusion-weighted imaging abnormalities in the splenium after seizures.

Joel Oster·Colin Doherty·P Ellen Grant·Mirela Simon·Andrew J Cole

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Abstract

PURPOSE: Transient increased T2 signal in the splenium of the corpus callosum after seizures has been reported and sometimes attributed to a postulated toxicity of anticonvulsant medications (AEDs). METHODS: We describe two patients with bitemporal epilepsy. RESULTS: Transiently increased T2 signal (in one) and decreased apparent diffusion coefficient (ADC) (in both) in the splenium appeared to be related directly to acute seizures. CONCLUSIONS: These cases illustrate an unusual acute postictal imaging finding, highlight involvement of an important commissural pathway, and suggest that seizures per se, and not their treatment, are the cause of transient white-matter abnormalities in these cases.

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Acute Disease Adult Anticonvulsants Corpus Callosum Diffusion Magnetic Resonance Imaging Electroencephalography Epilepsy, Temporal Lobe Follow-Up Studies Functional Laterality Humans Male Videotape Recording Case Reports Journal Article

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Joel Oster, Colin Doherty, P Ellen Grant, Mirela Simon, Andrew J Cole. 2003. Diffusion-weighted imaging abnormalities in the splenium after seizures.. https://doi.org/10.1046/j.1528-1157.2003.40902.x

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