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PubMed · 12702200

Statistical tests for differential expression in cDNA microarray experiments.

Xiangqin Cui·Gary A Churchill
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Abstract

Extracting biological information from microarray data requires appropriate statistical methods. The simplest statistical method for detecting differential expression is the t test, which can be used to compare two conditions when there is replication of samples. With more than two conditions, analysis of variance (ANOVA) can be used, and the mixed ANOVA model is a general and powerful approach for microarray experiments with multiple factors and/or several sources of variation.

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Analysis of VarianceGene Expression ProfilingMatched-Pair AnalysisOligonucleotide Array Sequence AnalysisStatistics as TopicJournal ArticleReview

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Xiangqin Cui, Gary A Churchill. 2003-03-17. Statistical tests for differential expression in cDNA microarray experiments.. https://doi.org/10.1186/gb-2003-4-4-210

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