Search PubMed⌕ Search
Home/Archive/PubMed

PubMed · 12526752

Evolution and disease.

Nigel Williams
View original source ↗Export metadata ↓

Abstract

A recent meeting highlighted how much Darwinian thinking on natural selection illuminates the background to some major current human diseases and may offer insight into many more. Nigel Williams reports on a field seeking a place in mainstream medical education.

Explore related subjects

Acquired Immunodeficiency SyndromeAfrica, WesternAnemia, Sickle CellAnimalsBiological EvolutionDiseaseGenetic Predisposition to DiseaseGenetics, PopulationHeterozygoteHumansMalariaMutationPapua New GuineaPlasmodium falciparumPlasmodium vivaxThalassemiaConference Proceedings

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Nigel Williams. 2003-01-08. Evolution and disease.. https://doi.org/10.1016/s0960-9822(02)01375-1

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2003

Post-kala-azar dermal leishmaniasis associated with AIDS.

Post-kala-azar dermal leishmaniasis (PKDL) is rarely reported in South America. In spite of the fact that there are many reports about the association of visceral leishmaniasis and AIDS, PKDL is very uncommon in HIV-positive patients, and so far only four cases have been documented in the literature. We present another case with unusual clinicopathological aspects. The patient, a 28-year-old male, from Salvador, Bahia (an endemic area) presented with clinical manifestations of visceral leishmaniasis three years after the diagnosis of AIDS. During treatment for visceral leishmaniasis he developed disseminated miliary papules. Microscopically, the skin biopsy showed a "saw-tooth" pattern with a lichenoid mononuclear infiltrate simulating lichen planus. The histopathological diagnosis was achieved through the finding of amastigotes. The authors discuss the clinicopathological aspects of this case based on a review of the specific literature.

Acquired Immunodeficiency Syndrome↗