Membrane biochips.

Ye Fang; Anthony G Frutos; Brian Webb; Yulong Hong; Ann Ferrie; Fang Lai; Joydeep Lahiri

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PubMed · 12514931

Membrane biochips.

Ye Fang·Anthony G Frutos·Brian Webb·Yulong Hong·Ann Ferrie·Fang Lai·Joydeep Lahiri

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Abstract

Membrane-bound proteins represent the single most important class of drug targets. This article discusses the issues surrounding fabrication of membrane-protein microarrays by conventional robotic pin printing techniques. Ligand binding selectivity and specificity to G protein-coupled receptor (GPCR) microarrays are presented. The potential applications of these arrays for drug screening are discussed.

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Equipment Design Equipment Failure Analysis Feasibility Studies GTP-Binding Proteins Humans Ligands Membrane Proteins Membranes, Artificial Protein Array Analysis Proteins Receptors, Adrenergic, beta-1 Receptors, Cell Surface Receptors, Dopamine D1 Receptors, Neurotensin Evaluation Study Journal Article Validation Study

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Ye Fang, Anthony G Frutos, Brian Webb, Yulong Hong, Ann Ferrie, Fang Lai, Joydeep Lahiri. 2002. Membrane biochips.. https://pubmed.ncbi.nlm.nih.gov/12514931/

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