Structure and function of the Arp2/3 complex.

Thomas D Pollard; Christopher C Beltzner

doi:10.1016/s0959-440x(02)00396-2

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Structure and function of the Arp2/3 complex.

Thomas D Pollard·Christopher C Beltzner

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Abstract

The Arp2/3 complex, a 220 kDa macromolecular assembly comprising two actin-related proteins and five other subunits, plays a key role in cellular motility by initiating the polymerization of new actin filaments. Crystal and cryo-electron microscopic structures of the Arp2/3 complex and branch junctions have clarified extensive biochemical data on the mechanism of this process.

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Thomas D Pollard, Christopher C Beltzner. 2002. Structure and function of the Arp2/3 complex.. https://doi.org/10.1016/s0959-440x(02)00396-2

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