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PubMed · 1242414

Do volunteer donors decrease posttranfusion hepattis?

P W Holley·G C Glenn·B Y Linkenhoker
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Abstract

A change from a paid to a volunteer blood donor system was instituted as recommended by the American Association of Blood Banks "Statement on the National Blood Policy." The incidence of counterelectrophoresis HBSAg positive units from each donor group was determined. Of 2,785 purchased units, 3 (0.10%) were HBSAg positive, while 34 (0.94%) of 3,609 units from volunteers were HBSAg positive. This 840% increase suggests that careful selection of donor population rather than blind reliance on volunteers should be emphasized in providing the safest blood for transfusion.

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Blood BanksBlood DonorsCounterimmunoelectrophoresisHepatitis BHepatitis B AntigensHumansMilitary MedicineTransfusion ReactionUnited StatesComparative StudyJournal Article

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P W Holley, G C Glenn, B Y Linkenhoker. 1975-12-08. Do volunteer donors decrease posttranfusion hepattis?. https://pubmed.ncbi.nlm.nih.gov/1242414/

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Regional transfusion centre preoperative autologous blood donation programme: the first two years.

OBJECTIVE: To assess the efficacy of a regional autologous blood donation programme. DESIGN: Clinical and laboratory data were collected and stored prospectively. Transfusion data were collected retrospectively from hospital blood bank records. SETTING: Northern Region Blood Transfusion Service and 14 hospitals within the Northern Regional Health Authority. SUBJECTS: 505 patients referred for autologous blood donation before elective surgery. MAIN OUTCOME MEASURES: Patient eligibility, adverse events from donation, autologous blood units provided, and autologous and allogeneic blood units transfused within 10 days of operation. RESULTS: Of 505 patients referred, 354 donated at least one unit. 78 of 151 referred patients who did not donate were excluded at the autologous clinic, mostly because of anaemia or ischaemic heart disease. In 73 cases the patient, general practitioner, or hospital consultant decided against donation. 363 autologous procedures were undertaken. In 213 (59%) cases all requested units were provided. The most common reasons for incomplete provision were late referral or anaemia. Adverse events accompanied 24 of 928 donations (2.6%). Transfusion data were obtained for 357 of the 363 procedures. 281 donors were transfused; autologous blood only was given to 225, autologous and allogeneic blood was given to 52, and allogeneic blood only was given to four. 648 of 902 (72%) units of autologous blood were transfused. Complete provision of requested autologous units was followed by allogeneic transfusion in 12 of 208 procedures (5.8%). Incomplete provision was followed by allogeneic transfusion in 44 of 149 procedures (30%). CONCLUSIONS: This study shows the feasibility of a regional autologous transfusion programme. Autologous donors only infrequently received allogeneic transfusion. Patients should be appropriately selected and referred early.

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