Search PubMed⌕ Search

PubMed · 11949518

Data mining methods for improving birth outcomes prediction.

Abstract

Data mining is a research method that is increasingly being used to predict clinical outcomes, for example, cancer or AIDS survival, diagnostic accuracy in abdominal pain or brain tumors, and much more. In clinical practice, predicting which patients will deliver preterm versus full term remains a complex clinical problem for families and the healthcare system. Exploratory data mining was used for predicting birth outcomes in a racially diverse sample (n = 19,970). Duke University provided data (1622 variables) for data mining methods that found 7 demographic variables yielded .72 area under the curve for receiver operating characteristic (ROC) analyses, suggesting that a parsimonious set of preterm birth outcomes predictors may be possible. Improved prediction is needed for interventions to be appropriately targeted for improved birth outcomes management.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Linda K Goodwin, Mary Ann Iannacchione. Data mining methods for improving birth outcomes prediction.. https://pubmed.ncbi.nlm.nih.gov/11949518/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Performance of the FearID earprint identification system.

The Forensic Ear Identification (FearID) research project was started in order to study the strength of evidence of earprints found on crime scenes. For this purpose, a sample of earprints from 1229 donors over three countries was collected. From each donor three left and three right earprints were gathered. On the one hand, operators denoted contours of the earprints to facilitate segmentation of the images, on the other anthropological specialists denoted anatomically specific locations. On the basis of this, methods for automated classification were developed and used for training of a system that classifies pairs of prints as 'matching' or 'non-matching'. Comparing lab quality prints, the system has an equal error rate of 4%. Starting from a reference database containing two prints per ear, hitlist behaviour is such that in 90% of all query searches the best hit is in the top 0.1% of the list. The results become less favourable (equal error rate of 9%) for print/mark comparisons.

Databases, Factual↗

Normal limits of ejection fraction and volumes determined by gated SPECT in clinically normal patients without cardiac events: a study based on the J-ACCESS database.

PURPOSE: Quantitative gated single-photon emission computed tomography (SPECT) is known to have high accuracy and precision for measurement of the principal cardiac functional parameters. We hypothesised that normal values for EF and LV volumes may differ among nationalities, and that optimal threshold values specific to the study population are required. METHODS: Among 4,670 consecutively registered patients for a J-ACCESS (Japanese investigation regarding prognosis based on gated SPECT) study from 117 hospitals, a total of 268 (149 women, 119 men) were selected who had no baseline cardiac diseases and had experienced no cardiac events during the preceding 3-year period. A gated SPECT study was performed with 99mTc-tetrofosmin and analysed with Cedars Sinai Medical Center's quantitative gated SPECT (QGS) software. The results in respect of ejection fraction (EF), end-diastolic volume (EDV), end-systolic volume (ESV) and stroke volume (SV), and EDV, ESV and SV normalised by body surface area (EDVI, ESVI and SVI), were calculated and summarised to obtain normal limits. RESULTS: EF for women and men was 74 +/- 9% and 63 +/- 7%, respectively (p < 0.0001). EDV, ESV and SV were significantly smaller in women than in men. Based on multiple regressions for linear models, the primary and secondary predictors of EF, EDVI, ESVI were gender and age. By stepwise multiple regression analysis, a statistically significant third predictor for EDV, ESV, SV and SVI was body weight. No colinearity was found between age and body weight. Important factors for the studied Japanese population included a high incidence of small hearts in women and the relatively advanced age of the population (the mean age +/-SD was 64.1 +/- 10.0 years for women and 60.9 +/- 11.7 years for men). CONCLUSION: EF and volumes determined by gated SPECT with QGS were significantly affected by gender and age, with body weight as a third predictor for volumes. Moreover, the normal limits were so specific for the population studied that standards appropriate for the study in question should be utilised.

Databases, Factual↗