Microscope-based techniques to study cell adhesion and migration.

Partha Roy; Zenon Rajfur; Pawel Pomorski; Ken Jacobson

doi:10.1038/ncb0402-e91

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Microscope-based techniques to study cell adhesion and migration.

Partha Roy·Zenon Rajfur·Pawel Pomorski·Ken Jacobson

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Abstract

Modern light microscopy has evolved to provide a variety of quantitative imaging techniques and also the capability to perturb structure-function relationships in living cells. The advances have been especially useful in the study of cell adhesion and migration. This review will focus on how such microscopy-based techniques can be useful in situ to study the molecular interactions and dynamics, to locally perturb actin-based structures and to measure the traction forces exerted by motile cells.

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Actins Biological Transport Cell Adhesion Cell Movement Cytological Techniques Energy Transfer Humans Light Microscopy Models, Biological Spectrometry, Fluorescence Journal Article Research Support, U.S. Gov't, P.H.S.Review

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Partha Roy, Zenon Rajfur, Pawel Pomorski, Ken Jacobson. 2002. Microscope-based techniques to study cell adhesion and migration.. https://doi.org/10.1038/ncb0402-e91

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