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Modular complexes that regulate actin assembly in budding yeast.

B L Goode·A A Rodal
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Abstract

The actin cytoskeleton of budding yeast contains an extensive set of actin-associated proteins with conserved mammalian counterparts. For more than 20 years, yeast has been used as a model organism to dissect the in vivo functions of these factors, revealing an intricate web of genetic interactions in the cell. Now, a surge of biochemical reports is defining the physical interactions and activities of these proteins and providing mechanistic insights into their cellular roles. The emerging view is that most actin-associated proteins do not act alone but, rather, associate to form modular protein complexes that regulate actin assembly and organization.

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ActinsCytoskeletonSaccharomycetalesStructure-Activity RelationshipJournal ArticleResearch Support, Non-U.S. Gov'tReview

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B L Goode, A A Rodal. 2001. Modular complexes that regulate actin assembly in budding yeast.. https://doi.org/10.1016/s1369-5274(01)00272-7

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