Omega-3 fatty acids decrease protein kinase expression in human breast cancer cells.

N G Moore; F Wang-Johanning; P L Chang; G L Johanning

doi:10.1023/a:1017968029628

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Omega-3 fatty acids decrease protein kinase expression in human breast cancer cells.

N G Moore·F Wang-Johanning·P L Chang·G L Johanning

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Abstract

We report that 5-day exposure to physiological concentrations of eicosapentaenoic and docosahexaenoic acids resulted in a strong decrease in expression of the RIalpha regulatory subunit of protein kinase A and the PKC-alpha isozyme of protein kinase C in the human breast cancer cell line MDA-MB-231.

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Arachidonic Acids Breast Neoplasms Cyclic AMP-Dependent Protein Kinases Docosahexaenoic Acids Female Gene Expression Regulation, Neoplastic Humans Isoenzymes Protein Kinase C Tumor Cells, Cultured Journal Article Research Support, Non-U.S. Gov't

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N G Moore, F Wang-Johanning, P L Chang, G L Johanning. 2001. Omega-3 fatty acids decrease protein kinase expression in human breast cancer cells.. https://doi.org/10.1023/a%3A1017968029628

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